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Author

Hong-Yu Bao

2 papers indexed here

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Open access Sep 2026

Shared-Output Aptamer-Gated DNA Nanodevices Program NbaSPARDA Trans-Cleavage for Metabolite and Drug Sensing.

Routing chemically distinct small-molecule aptamers into a common nuclease trans-cleavage pathway is constrained by the target-specific output handles of conventional structure-switching aptamers (SSAs). Shared-output aptamer-gated DNA nanodevices are designed so that recognition cores control release of the same short...

Yi Du, Yu Shen, Shao-Yu Yang et al. · 0 citations
Open access Aug 2026

Photodynamically Sensitized Mitochondrial-Damage Amplification Strategy Promotes Pyroptosis-Induced Immunotherapy of Osteosarcoma

The heterogeneity of osteosarcoma (OS) is the main reason for ineffective treatment and uncontrolled disease. Immunotherapy provides an ideal strategy to overcome the heterogeneity of OS, but effective activation of tumor-intrinsic immunogenicity remains challenging. We developed a biomimetic nanoplatform utilizing mit...

Tao Ding, Tong-Yin Xiong, Xin-Zhong Xu et al. · 0 citations

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