PRRSV infection induces mitochondrial damage and releases mitochondrial dsRNA to activate the NLRP3-dependent inflammatory response
Porcine reproductive and respiratory syndrome (PRRS), caused by the PRRS virus (PRRSV), remains one of the most economically significant infectious diseases affecting the global swine industry, resulting in annual losses exceeding US $1.2 billion in the USA alone. PRRSV infects porcine alveolar macrophages (PAMs) and i...