B-418 Simultaneous LC-MS/MS quantification of Cefepime, Meropenem, Piperacillin and Tazobactam in pediatric serum: method validation for therapeutic drug monitoring
ß-lactam antibiotics and ß-lactamase inhibitors are cornerstone therapies for serious pediatric infections, yet drug exposure in children is highly variable due to developmental pharmacokinetics, critical illness, and rapidly changing renal function. Underexposure can contribute to treatment failure, while overex...