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Hongxia Li

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Open access Oct 2026

Neuromedin B Regulates Cell Proliferation, Apoptosis and Steroidogenesis of Porcine Ovarian Granulosa Cells via NMBR

Simple Summary Neuromedin B is a naturally occurring signaling molecule that may be involved in the regulation of ovarian function, but its role in the pig ovary is not well understood. This study examined where the receptor for neuromedin B is located in the pig ovary and investigated how neuromedin B affects granulos...

Zhi-Yu Ma, Hong-Xia Li, Guang-Zhen Chen et al. · 0 citations
Aug 2026

Effects and mechanisms of NMB knockdown on cell proliferation, apoptosis and steroidogenesis in porcine ovarian granulosa cells.

Findings suggest that NMB may serve as an important regulator of cell viability, apoptosis and steroidogenesis through mitochondrial Ca2+ uptake and the PKA/CREB axis in GCs, thereby providing new mechanistic insights into follicular development and potential targets for improving porcine reproductive efficiency.

Hongxia Li, Guang-Zhen Chen, Jia Li et al. · 0 citations

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