Sep 2026
MMSDH facilitates ACSL4 propionylation to counteract ferroptosis upon hypoxia and impairs PDAC chemotherapy efficacy.
Pei-Xiang Zheng, Yan-Ni Lin, Mei-Yin Zhang et al.
· Nature Cancer · 0 citations
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Open access
Aug 2026
UBA1 enhances phagocytosis by suppressing CD47 expression in small cell lung cancer
Introduction Small cell lung cancer (SCLC) exhibits a limited overall response rate to immunotherapy, largely due to its highly immunosuppressive microenvironment. CD47, an innate immune checkpoint frequently overexpressed on SCLC cells, contributes to immune evasion by inhibiting macrophage-mediated phagocytosis. Here...
Dong-Yu Li, Na Li, Yiqiang Liu et al.
· Frontiers in Oncology · 0 citations