Open access
Sep 2026
INHBB Promotes Colorectal Cancer Progression by Inducing CD8 + T Cell Exhaustion via the ACVR2B‐SMAD Signaling Axis
ABSTRACT To investigate the expression pattern, biological functions and regulatory mechanisms of inhibin beta B (INHBB) in colorectal cancer (CRC), and to clarify its role in mediating CD8+ T cell exhaustion via the INHBB‐ACVR2B‐SMAD signaling axis for identifying a novel therapeutic target in CRC targeted immunothera...
Guang-Hui Liu, Yuan-Hua Liu, Hong-Chao Zhao et al.
· Cancer Science · 0 citations