Author

Hong-Su Zhao

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Dec 2026

Paeonia lactiflora pall. Polysaccharide attenuates inflammation and improves intestinal barrier function in ulcerative colitis mice by modulating intestinal flora and inhibiting S100A8/A9/NF-κB signaling.

Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) with substantial clinical burden and limited treatment options. PLPN-2, an α-glucan extracted from P. lactiflora, has shown anti-inflammatory activity in cellular and animal models, but its therapeutic mechanisms in UC remain unclear. Here, mice were...

Pei-Pei Li, Hong-Su Zhao, Xiang-Ming Jiang et al. · Food Research International · 0 citations

Open access Sep 2026

Aqueous extract of Paeoniae Radix Alba alleviates DSS-induced ulcerative colitis via inhibition of the IFN-γ/JAK1/STAT1 signaling pathway and restoration of intestinal barrier function.

BACKGROUND Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by aberrant immune activation and intestinal microenvironment dysregulation. Paeoniae Radix Alba (RPA), a classic traditional Chinese medicine (TCM) derived from the roots of Paeonia lactiflora, possesses potent anti-inflammatory,...

Rong-Yun Cao, Mei-Juan Sun, Min Pan et al. · Phytomedicine · 0 citations

Open access Oct 2026

Homoisoflavanones, Alkaloid, and Norsesquiterpenoid from Polygonatum cyrtonema and Their Immunomodulatory Effects

Polygonatum cyrtonema (Huang jing) is widely used in both the food and traditional Chinese medicine industries. A chemical investigation of the rhizome of cultivated P. cyrtonema yielded six previously undescribed compounds─one norsesquiterpenoid (1), one pyridine alkaloid (2), and four homoisoflavanones (3a, 4a, 5a,...

Hong-Su Zhao, Cai-Xia Lu, Fu-Cai Ren et al. · ACS Omega · 0 citations