Author

Hong-Rui Zhang

2 papers indexed here

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Review Open access Sep 2026

Cuproptosis in Cerebrovascular Diseases: Mechanisms and Advances in Targeted Therapeutic Strategies.

Cuproptosis is a recently identified form of regulated cell death. It is primarily driven by abnormal mitochondrial copper accumulation. Ferredoxin 1-dependent copper reduction promotes the pathological aggregation of lipoylated proteins involved in the tricarboxylic acid cycle and the loss of iron-sulfur cluster prote...

Xin-Yi Zhang, Ru-Fan Xu, Hong-Rui Zhang et al. · Brain Research Bulletin · 0 citations

Sep 2026

A novel conformationally constrained RGD-based cyclic peptide targeting integrin αvβ6 protein for antitumor therapeutic applications.

Comprehensive in vitro and in vivo biological evaluations revealed that cyclic peptide effectively suppresses tumor cell proliferation and induces both apoptosis and autophagy.

Yang Lv, Chun-Yu Qu, Yue Lei et al. · Chemico-Biological Interacti... · 0 citations