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Author

Hong-Qing Cai

2 papers indexed here

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Open access Oct 2026

TOP2A Overexpression as a Prognostic Biomarker in High-Grade Meningioma: An Integrated Single-Cell and Bulk Transcriptomic Study

By integrating transcriptional overexpression with copy-number gain, this study identifies TOP2A mRNA and protein overexpression as a prognostic biomarker in high-grade meningioma and shows that focal TOP2A copy-number gain is enriched in high-grade tumors and concordant with TOP2A expression.

Hong-Qing Cai, Guan-Chao Xie, Hou-Jie Liu et al. · 0 citations
Open access Sep 2026

Neurosurgical Resection for De Novo Brain Metastases from Non-Small Cell Lung Cancer: Real-World Evidence for Multidisciplinary Decision-Making

Background: Patients presenting with concurrent lung and brain lesions pose a unique diagnostic and therapeutic challenge. The role of neurosurgical resection in the management of de novo non-small-cell lung cancer brain metastases (NSCLC-BM) remains poorly defined. Methods: Consecutive patients undergoing resection fo...

Xin-Yu Wang, Hong-Liang Mao, Feng-Chun Mu et al. · 0 citations

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