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Hong Kong

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Open access Sep 2026

Smallpox Vaccine Elicits CD8+ T Cell Immunity Persisting Over Four Decades with Cross-Recognition of Monkeypox Virus

Monkeypox, caused by MPXV, has become a global public health concern; however, the T-cell immunity against MPXV following smallpox vaccination remains unclear. In this study, we screened the immunogenicity of 21 predicted MPXV epitopes and compared immune responses between young and elderly groups. Two immunogenic CD8⁺...

Yu-Juan Du, Zong-Mian Yang, Yin-Ying Xiao et al. · 0 citations

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