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Hong-Ji Li

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Sep 2026

ALKBH5-Dependent m6A Demethylation Promotes Cardiac Aging Through SLC38A3 Reduction and Glutamine Metabolic Alteration.

BACKGROUND N6-methyladenosine (m6A) modification has been linked to various types of physiological and pathological bioprocesses. However, the exact role of m6A mRNA methylation in cardiac aging is largely unknown. Here, we show that ALKBH5 (alpha-ketoglutarate-dependent dioxygenase AlkB homolog 5), an m6A demethylase,...

Kun Liu, Chi-Qian Liang, Hong-Ji Li et al. · 0 citations

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