Hong-Chao Zhou

Endoplasmic reticulum stress activated by IBRV induces mitophagy to impair the RIG-I-MAVS-mediated type I interferon pathway and facilitate viral replication.

Infectious bovine rhinotracheitis (IBR) is a globally recognized infectious disease. The causative agent infects the respiratory and reproductive tracts of cattle, resulting in substantial economic losses to the cattle industry. Endoplasmic reticulum stress (ERS) and mitophagy play critical roles in maintaining cellula...