Swine influenza virus (SIV) poses a continuous threat to global pig production and public health. Efficient SIV replication is highly dependent on host factors, making their identification and functional characterization important for the development of host-directed antiviral strategies. Here, we investigated the role...
Hui-Min Sun, Di-Dan Luo, Shao-Yu Tu et al.· Microbiology Research· 0 citations
This work defines DDX10 as a potential host factor that differentially supports influenza polymerase activity, revealing a specific molecular interface that contributes to the replication efficiency of distinct viral subtypes in human cells and providing insight into host-adaptive mechanisms.
R. Ullah, Wei Chen, Ling-Kai Zhang et al.· Journal of Virology· 0 citations
These findings define two novel, nonneutralizing epitopes on H9N2 HA that expand the antigenic map and represent promising targets for subtype-specific diagnostic assays.
The structure of PEDV HNXX-strain spike domain B (S1B) is determined and a strain-specific vulnerable site on the PEDV S-trimer is identified, providing insight into how cell-surface membrane fusion activity may influence viral entry pathway selection and antibody neutralization efficacy.
Jian-Bo Liu, Sheng Wang, Zi-Mu Li et al.· bioRxiv· 0 citations
The findings uncover a previously unrecognized role of RBM6 in shaping influenza virus replication and highlight the RBM6-M901C axis may serve as potential targets for controlling influenza virus adaptation and interspecies transmission.
Jia-Hui Zou, Shao-Yu Tu, Hui-Min Sun et al.· bioRxiv· 0 citations
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