Author

Hong-Bo Guo

2 papers indexed here

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Aug 2026

TAGLN2 promotes mesenchymal circulating tumor cell-associated metastasis through the CSNK1E-YAP Axis with concomitant EMT induction and metabolic remodeling in hepatocellular carcinoma.

Postoperative recurrence and hematogenous metastasis remain major barriers to long-term survival in hepatocellular carcinoma (HCC). Mesenchymal circulating tumor cells (mCTCs) are closely associated with HCC recurrence and metastasis, yet the key regulatory mechanisms and accompanying circulating metabolic alterations...

Lei Luo, Zhuohao Chen, Junxi Chen et al. · Cellular Signalling · 0 citations

Sep 2026

Genetic Determinants of Vascular Dementia: Blood Metabolite Associations and Candidate Therapeutic Target Prioritization.

Vascular dementia (VaD), caused by reduced cerebral blood flow, is a common form of dementia lacking effective treatments. This study used genome-wide association study (GWAS) summary data, Mendelian randomization (MR), and colocalization analyzes to prioritize blood metabolites and candidate therapeutic targets associ...

Cheng-Wei Chen, Xiang Zou, Jie Hu et al. · Genetic Epidemiology · 0 citations