Aug 2026
Multi-omics and experimental validation reveal the proliferative mechanism of ACSL4 in pulmonary hypertension and identify potential FDA-approved drugs via in silico screening.
A novel mechanism by which ACSL4 fuels PASMC growth in PH through reshaping fatty acid metabolism and targeting the VGLL4/YAP signaling axis is uncovers.
Wei Chen, Yi-Ting Dong, Qiong Shi et al.
· Vascular pharmacology · 0 citations