Prion-like transmission of human tau strains in the mouse brain
Abstract Most neurodegenerative diseases are thought to spread through the brain by prion-like mechanisms, in which filamentous protein assemblies self-propagate by templated seeding 1 . Distinct conformations of amyloid filaments may provide the physical basis for the strains that lead to different diseases 2 . Howeve...
Sofia Lövestam, Aki Shimozawa, Airi Tarutani et al.
· Nature · 1 citation