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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Hiromasa Kaneko

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Open access Sep 2026

Comprehensive microRNA profiling coupled with function-based feature selection reveals a biomarker panel for predicting CAR-T cell exhaustion.

Chimeric antigen receptor (CAR)-T cell exhaustion limits durable therapeutic efficacy, particularly under persistent antigen stimulation. While transcriptomic and epigenomic analyses have advanced the understanding of CAR-T cell exhaustion, the contribution of microRNAs (miRNAs) remains poorly characterized. Here, we p...

Noriko Nakamura, Hyemin Seo, Risa Hamada et al. · 0 citations

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