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Hirofumi Kosuge

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Open access Sep 2026

Reversible homodimerization of a small leucine-rich proteoglycan PRELP modulates the interactions with TGFβ1 and IGFI-R.

Small leucine-rich proteoglycans (SLRPs) are responsible for various biological functions via their multiple interactions with various proteins. Although some SLRPs form homodimers, it remains unclear how homodimerization affects the molecular functions of SLRPs. Herein, we report the molecular basis and functional sig...

Hirofumi Kosuge, M. Nakakido, Daisuke Kuroda et al. · 0 citations

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