The CENP-A chaperone complex spatially organizes centromeres
Centromeres, defined by CENP-A–containing nucleosomes, direct kinetochore assembly for spindle attachment. In mitosis, CENP-A and the constitutive centromere-associated network (CCAN) of the inner kinetochore are arranged into bipartite subdomains within clearings of chromatin. However, less is known about their archit...