BACKGROUND
Allogeneic hematopoietic cell transplantation (HCT) is the only curative therapy for myelofibrosis (MF), and donor selection remains one of the few modifiable determinants of outcome. As the unrelated donor pool ages, the impact of donor age in matched unrelated donor (MUD) HCT for MF has become increasingly...
K. Sakatoku, Yutaka Shimazu, Makoto Murata et al.· Transplantation and Cellular...· 0 citations
Although recent studies suggested an enhanced graft-versus-tumor (GVT) effect with cord blood transplantation (CBT), higher rates of engraftment failure, acute graft-versus-host disease (GVHD), and infections, including cytomegalovirus (CMV), contribute to increased nonrelapse mortality (NRM). Thus, further optimizatio...
Shunto Kawamura, Y. Akahoshi, Hideaki Nakasone et al.· Transplantation and Cellular...· 0 citations
Th17, a subset of helper T cells that produce interleukin-17 (IL-17), is thought to play a pivotal role in the pathogenesis of chronic graft-versus-host disease (GVHD). However, the kinetics of Th17 following allogeneic haematopoietic stem cell transplantation (allo-HSCT) have not been elucidated. In this study, we eva...
M. Tamaki, Hideaki Nakasone, Shunto Kawamura et al.· British Journal of Haematolo...· 0 citations