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Author

Hiba Narvel

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Review Open access Sep 2026

The Multifaceted Roles of STAT6: Implications for Precision Immunotherapeutics

Abstract STAT6, located on chromosome 12, encodes a transcription factor whose SH2 domain is central to its activation. While classically a Th2 mediator, aberrant STAT6 activation is observed in diverse malignancies. This review focuses on the molecular and functional landscape of STAT6, primarily in cancer and tumor i...

Hiba Narvel, D. Nishizaki, S. Kato et al. · 0 citations

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