Association of DNMT3A Polymorphism, Oxidative Stress, and Global DNA Methylation in Type 2 Diabetes Mellitus Patients.
BACKGROUND/AIMS DNA methylation is a critical epigenetic mechanism involved in the regulation of gene expression, including genes implicated in glucose metabolism. Despite growing evidence indicating that epigenetic mechanisms are involved in the pathogenesis and progression of type 2 diabetes mellitus (T2DM), availabl...