Author

Herbert Pang

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Review Open access Oct 2026

Addressing Missing Data in Clinical Trials With a Hybrid Control Arm

ABSTRACT Randomized trials have long been the standard for evaluating experimental treatments in medical and pharmacological studies, but the associated time and cost have spurred research into designs that augment randomized studies with data from external sources. Hybrid control arms offer the promise of improved pre...

Josh Wasserman, Herbert Pang, Jia-Wen Zhu · Statistics in Medicine · 0 citations

Open access Aug 2026

Empowering Clinical Development With Disease Progression Modeling: Recommendations From the Clinical Trials Transformation Initiative

Evaluating the benefit–risk profile of a medical product requires comprehensive evidence that integrates information across development stages. Technological advances and broader use of real‐world data are enabling innovative quantitative paradigms characterized by greater efficiency, patient centricity, and sustainabi...

Lindsay Kehoe, Shu Chin Ma, Jiang Liu et al. · Clinical and Translational S... · 0 citations