Background Deficits in inhibitory control are considered a central feature of alcohol use disorder (AUD), yet behavioral and neuroimaging findings have been inconsistent. One potential explanation is the marked heterogeneity of AUD, which encompasses multiple symptom dimensions that may differ in their underlying neuro...
J. Böhmer, Pablo Reinhardt, Marco Bottino et al.· bioRxiv· 0 citations
This study evaluated the latent structure and conceptual validity of the Research Domain Criteria (RDoC), General Health, and Clinical/Psychosocial clusters of the German Center for Mental Health (DZPG) Minimum Data Set (MDS). It aimed to determine whether these clusters represent interpretable constructs and demonstra...
Bernd R. Förstner, S. Böttger, Timm Seegert et al.· European Archives of Psychia...· 0 citations
Alcohol-related cues are thought to contribute to drinking in alcohol use disorder (AUD), but their contribution in daily life remains difficult to separate from changing social contexts and internal states. We used ecological momentary assessment in two independent cohorts of non-treatment-seeking individuals, compris...
A. Ghadami, Abhijit Sreepada, I. Reinhard et al.· Translational Psychiatry· 0 citations
Changes in personality during adolescence may shape future alcohol use, especially in times of societal crisis. The COVID-19 pandemic disrupted social norms and stress regulation, making it a natural experiment to examine how early-life personality trajectories predict later substance use. Using longitudinal data from...
Rabia Zohair, K. Janson, Sebastian Siehl et al.· Scientific Reports· 0 citations
Early detection and prevention of psychiatric disorders, particularly depression, remain as major global health challenges, yet reliable tools for identifying individuals before symptom onset are lacking. Here, we combine functional neuroimaging with computational modeling to identify a mechanistic biomarker of depress...
Han Lu, Xiaoqian Yan, Benjamin Becker et al.· Science Advances· 0 citations
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