Polylactic acid nanoparticles (PLA NPs) are widely used biodegradable plastics, but their potential health risks remain unclear. This study explores whether PLA NPs induce renal cell apoptosis through a mitochondrial pathway involving transient receptor potential melastatin 2 (TRPM2) and mitophagy. Adult male C57BL/6 m...
Pathogenic bacteria are related to clinical infections and high morbidity, and they pose significant diagnostic challenges for rapid testing. Loop-mediated isothermal amplification (LAMP) is a fast, convenient, and highly sensitive nucleic acid assay but remains challenging in complex matrices as well as in strategies...
Bo Yi, Dong-Gen Zhou, He-Nan Dong et al.· In Analysis· 1 citation
The 'metabolic vulnerability amplification model' is proposed, which posits that NPs do not act merely as independent metabolic toxins, but may amplify pre-existing metabolic stress, to compromise metabolic resilience.