Author

Heba M. Hesham

h-index 3 View on Semantic Scholar

We have 2 of 9 papers

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Open access Sep 2026

Design, synthesis, structure-activity relationship and in-silico studies of novel pyrazolo[1,5-a]pyrimidine derivatives as selective COX-2 inhibitors with promising anti-inflammatory activity and safety profile.

A novel series of pyrazolo[1,5-a]pyrimidine derivatives was designed using ligand-based pharmacophore modeling, and their structures were confirmed by 1H/13C NMR and LC-MS, establishing 8a and 8i as potent, selective, and structurally stable lead candidates for preclinical COX-2 inhibitor development.

Alaa Omar Mohamed Helmy, A. Taher, Eman Z. El Razaz et al. · Bioorganic chemistry (Print) · 0 citations

Aug 2026

Design and synthesis of novel thiazolotriazole-sulfonamide hybrids tackling antimicrobial resistance: mechanistic insights into efflux pump inhibitor, gene downregulation, and machine-aided results.

A novel series of thiazolotriazole-sulfonamide hybrids was designed using a molecular hybridization strategy anderve as promising candidates to overcome antimicrobial resistance.

Hossam H. Elsayed, Eman Z. Elrazaz, Maiy Y Jaballah et al. · Bioorganic chemistry (Print) · 0 citations