Structure-guided computational design of DNA tweezers for predicted recognition of the primary glioblastoma biomarkers S100A4 and midkine
Glioblastoma multiforme (GBM) is among the most aggressive malignant brain tumors and is characterized by severe infiltration into surrounding brain tissue, rendering early detection exceedingly difficult with current diagnostic imaging methods. Chosen biomarkers S100A4, with a role in cell motility and tumor metastasi...