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Hassan Hashimi

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Open access Sep 2026

Interconnections with and within the trypanosomal respiratory chain revealed by complexome profiling

Proteins are frequently integrated into multicomponent complexes that execute the elaborate processes supporting life. Thus, a protein’s function can only be defined by the company it keeps within a complex. Proteomes provide informative protein inventories but lack information about protein quaternary structures. Comp...

Corinna Benz, R. Khan, Michael Hammond et al. · 0 citations
Open access Jul 2026

Trypanosomal MICOS is assembled on non-respiring mitochondrial crista precursors and associates with two integral microproteins

It is demonstrated that all MICOS subunits assemble onto precursor cristae, retaining conserved interactions with both outer and inner membrane protein machineries, establishing that MICOS assembly precedes cellular respiratory competence and expand its interaction landscape in trypanosomatids.

Michala Boudová, Teresa Wagner, Tomáš Bílý et al. · 1 citation
Review Open access Aug 2026

The molecular mechanisms of crista formation: how mitochondria give themselves breathing room

The few knowns about crista formation in a handful of organisms are highlighted to guide research into the many unknowns about how complex subcompartments represented by mitochondrial cristae are formed.

Lilia Colina-Tenorio, Martina Bohuslavová, Alexander W. Bruce et al. · 0 citations

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