Background Two-drug antiretroviral regimens are increasingly explored to simplify HIV-1 treatment while maintaining durable viral suppression. Doravirine combined with Islatravir (DOR/ISL) represents a novel non-integrase strand transfer inhibitor (non-INSTI) regimen. However, comprehensive synthesized evidence remains...
M. Azam, M. Azam, Muhammad Arif Khan et al.· Therapeutic Advances in Infe...· 0 citations
Type 2 Diabetes Mellitus (T2DM) is a growing health burden globally, and its concurrence with Congestive Heart Failure (CHF) significantly increases morbidity and mortality. However, long‐term mortality trends remain underexplored. This study aims to assess temporal trends in mortality from comorbid T2DM and CHF in the...
Syeda Sameen Afzal, Ittiqa Khatri, Mariam Bahzad et al.· Health Science Reports· 0 citations
ABSTRACT Background Posterior circulation ischemic stroke (PCIS) is associated with substantial morbidity and mortality, and the optimal intravenous thrombolytic strategy in this subgroup remains unclear. Methods We searched databases for studies comparing intravenous tenecteplase with alteplase in adults with PCIS. Th...
Shaheer Bin Shafiq, A. Uddin, Muhammad Hussain et al.· Brain and Behavior· 0 citations
Obstructive sleep apnea (OSA) and respiratory failure (RF) represent increasing clinical and public health challenges in the United States, yet national trends in mortality remain underexplored. This study evaluates trends in mortality associated with OSA and RF to highlight targeted prevention and management across de...
M. Saghir, Eshal Saghir, Nida Shoaib et al.· Medicine· 0 citations
Coronary artery disease (CAD) is one of the major causes of death in the United States, whereas substance related conditions (SRC) are increasingly on the rise in the country. There is a paucity of information on national trends of CAD mortality over time with coexisting substance related conditions (SRC)....
M. Mustafa, Saifullah Khan, M. Saleem et al.· Journal of Epidemiology and...· 0 citations
Chronic obstructive pulmonary disease (COPD) and obesity are major US public health conditions that frequently coexist. Despite adverse respiratory and cardiometabolic effects of obesity, an apparent “obesity paradox,” whereby obesity has been associated with lower mortality in some patients with COPD, has been describ...
AM Khan, Syed Azfar Hussain, Z. Ahmad et al.· Medicine· 0 citations
Overall, adverse events were mild, transient, and comparable across vaccines and most included trials reported no serious adverse events (SAEs), indicating a favorable safety profile.
Muhammad Hussain, Muhammad Hassan, Abdul Hannan et al.· Frontiers in Public Health· 0 citations
The potential clinical relevance of CSP when a high ventricular pacing burden is anticipated remains plausible but was not directly demonstrated by the available data; adequately powered randomized trials are required before routine adoption.
R. Shakeel, A. Uddin, D. Ladhani et al.· Pacing and clinical electrop...· 0 citations
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