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Author

Harris E. Blankenship

2 papers indexed here

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Open access Sep 2026

PFKFB2 Gates a Relationship Between Cardiac Glycolytic Regulation and Electrophysiological Function.

BACKGROUND The cardiac isoform of PFKFB2 (phosphofructokinase-2/fructose 2,6-bisphosphatase) is the heart's strongest glycolytic regulator but is degraded in the absence of insulin signaling. This makes PFKFB2 loss critical to understand in metabolic heart disease, of which impaired insulin signaling is a hallmark. Pro...

Kylene M. Harold, Harris E. Blankenship, Keaton E. Minor et al. · 0 citations
Feb 2026

Pathogenic tau in the mouse locus coeruleus produces noradrenergic hyperactivity and neuropsychiatric phenotypes reminiscent of early Alzheimer’s disease

It is demonstrated that pTau triggers phenotypes reflective of LC-NE hyperactivity in the early stages of AD pathogenesis, laying the foundation for the development of LC-based disease-modifying therapies to address neuropsychiatric manifestations.

Anuradha Korukonda, Harris E. Blankenship, K. Kam et al. · 3 citations

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