Author

Haozhang Huang

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Open access Oct 2026

Association of Life’s Essential 8 and its components with adverse cardiovascular and kidney events in patients with atherosclerotic cardiovascular disease: a prospective cohort study

Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of global mortality. Despite advances in primary prevention and acute management, patients with established ASCVD face high residual risks for recurrent major adverse cardiovascular events (MACEs) and chronic kidney disease (CKD) progression. Life’...

Z. Yuan, X. Lu, G. Yuan et al. · European Heart Journal · 0 citations

Open access Aug 2026

Life's Essential 8 Score and Cardiovascular-Kidney Outcomes in ASCVD: A UK Biobank Prospective Cohort Study.

Higher LE8 scores were associated with lower risks of MACE and CKD in ASCVD patients, and high LE8 achievement may attenuate risks toward non-ASCVD levels.

Xiao-Zhao Lu, Zi-Yao Yuan, Guo-Shuai Yuan et al. · JACC: Advances · 0 citations

Open access Aug 2026

Integrated proteomic, transcriptomic, and epigenomic profiling identifies SRA1 as a novel therapeutic target for postpartum depression

This study reveals that SRA1 is a novel therapeutic target for PPD, which enhances the understanding of its molecular aetiology and the development of therapeutic strategies.

Ming Chen, Qinlin Wei, Hao-Wen Li et al. · npj Mental Health Research · 0 citations

Jul 2026

Sex-specific effects of depression on the incidence and risk factors for coronary heart disease: insights from multi-omics approaches.

Findings highlight significant sex differences in the effect of depression on CHD risk, which could inform sex-specific preventive strategies for reducing the cardiovascular burden in individuals with depression.

Haozhang Huang, Ming Chen, Xiao-Zhao Lu et al. · European Journal of Preventi... · 0 citations