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Author

Hao Zhang

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Open access Jul 2026

Manufacturing and electrostatic surface optimization of CAR-T cells improve therapeutic efficacy in liver malignancies.

Systematic optimization of manufacturing conditions and structure-based charge engineering of CAR constructs synergistically enhance therapeutic efficacy against liver malignancies, providing a translatable framework for improving solid tumor CAR-T therapy.

Linke Bian, Jiufei Zhu, Hong-Ye Wang et al. · 0 citations
Open access Jul 2026

An infection-responsive multifunctional hydrogel enables potent activity against methicillin-resistant Staphylococcus aureus and promotes wound healing

Gel-P@Z exhibited a slow and sustained release of Gly-POX and achieved >99% antibacterial efficacy against drug-resistant bacteria without toxicity, and RNA-seq analysis revealed that Gel-P@Z accelerated healing via upregulation of the TGF-β signaling pathway, driving fibroblast-to-myofibroblast transition and promotin...

Chuanliang Fu, Wenjing Zhang, Ren-Yuan Wang et al. · 0 citations

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