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Open access Sep 2026

The Secretome Derived From Human Umbilical Cord Mesenchymal Stem Cells Improves Skin Photoaging by Enhancing Mitophagy to Inhibit the cGAS‐STING Pathway

Ultraviolet (UV)‐induced skin photoaging is driven by cellular senescence and chronic inflammation. Although the secretome (SCT) derived from human umbilical cord mesenchymal stem cells (hUC‐MSC SCT) exhibits regenerative potential, its role in combating photoaging remains to be elucidated. In this study, we show that...

Ting-Ting Tang, Mei-Feng Lin, Jing-Jing Yang et al. · 0 citations
Open access Aug 2026

Elucidating adverse drug reactions and underlying molecular mechanisms of ivermectin through pharmacovigilance and multi-omics analysis

Objective The comprehensive safety profile and underlying molecular mechanisms of ivermectin-associated adverse drug reactions (ADRs) remain to be fully elucidated. Methods We integrated pharmacovigilance data from the FDA Adverse Event Reporting System (FAERS) with network toxicology and transcriptomic validation. Dis...

Bo-Yi Liu, Xiao-Ze Chen, Yi-Shuo Wang et al. · 0 citations

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