Author

Hao-Yang Li

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Sep 2026

Combinatorial Metabolic and Process Engineering for Enhanced GA4+7 Production and Tunable GA4/GA7 Ratio in Fusarium fujikuroi.

This study demonstrated that the GA4/GA7 ratio can be modulated through both molecular and fermentation strategies, and engineering a high-yielding GA4+7 producer using this Δp450-3 mutant as a platform.

Jing-Wen Jia, Zheng-Bin Zhang, Ming-Han Li et al. · Biotechnology and Bioenginee... · 0 citations

Jul 2026

Beyond direct pathway engineering: reprogramming Fusarium fujikuroi from a GA3 producer into a GA4+7 factory.

This study achieves indirect metabolic reprogramming not via conventional pathway engineering, but by targeting a membrane transport bottleneck and employing a putative post-transcriptional silencing mechanism.

Hang Xiao, Tao-Xu Lu, Ming-Han-Li-Ming-Han Li et al. · Bioresource Technology · 1 citation