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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Hao Wu

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2 papers indexed here

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Sep 2026

Gut microbiota-mediated dietary lignans metabolism drives accumulation of N,N-dimethylsphingosine and sensitizes triple-negative breast cancer to paclitaxel.

Results indicate that DL potentiate PTX efficacy in TNBC, at least in part, through microbiota-dependent accumulation of DMS, offering a rationale for microbiota-informed strategies to optimize chemotherapy in TNBC.

Jian-Yu Wang, Liu-Ying Zhao, Shi-Lu Zhao et al. · 0 citations
Aug 2026

Targeted Degradation of ATP7B via a Novel Autophagy-Targeting Chimera Promotes Cuproptosis to Potentiate Anti-Tumor Immunity in Clear Cell Renal Cell Carcinoma.

The RNF186-p62-ATP7B axis is identified as a critical regulator of copper homeostasis in ccRCC and Targeting ATP7B via ATAUTAC offers a potent strategy to induce cuproptosis and sensitize ccRCC to immunotherapy.

Muyang Cao, Zhenkun Dong, Yang-Yang Xu et al. · 0 citations

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