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Author

Hao Wang

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Sep 2026

A miR-10a-5p-γCaMKII axis links periphery-to-brain signaling to cognitive vulnerability during female midlife.

Although women live longer, they paradoxically face heightened susceptibility to cognitive and systemic decline emerging in midlife-an underexplored transition from resilience to vulnerability. Here, we investigate biological processes associated with this female-biased vulnerability and their molecular regulation. Sen...

Jing Qu, Jing Yang, Wen-Wen Li et al. · 0 citations
Open access Sep 2026

ERK-dependent hyperexcitability of BLA neurons projecting to dCA3 underlies social dysfunction in a male mouse model of fragile X syndrome

A causal link from FMRP loss to circuit dysfunction and ERK pathway dysregulation is established, and it is suggested that targeting this pathway may offer a promising strategy for treating social dysfunction in ASD and FXS.

Si-Yu Wang, Xiao-Tong Wu, Si-Yuan Dong et al. · 1 citation

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