Author

Hao Wang

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Open access Oct 2026

Berberine ameliorates thioacetamide-induced liver injury in zebrafish through PPARγ signaling and restores bile acid homeostasis

Ethnopharmacological Relevance Coptis chinensis Franch. (Huanglian), a traditional Chinese medicinal herb used for “heat” and “dampness” syndromes, is clinically associated with metabolic disorders such as NAFLD. Berberine (BBR), its major bioactive alkaloid, has shown metabolic benefits, though its mechanistic basis i...

Peng Sun, Jun Wu, Xiao-Yu Zhu et al. · Frontiers in Pharmacology · 0 citations

Oct 2026

Sodium butyrate combined with ethanol-metabolizing Lactobacillus strains attenuates alcoholic liver disease by restoring gut-liver homeostasis.

Alcoholic liver disease (ALD) is characterized by hepatic lipid accumulation, inflammation, and intestinal barrier dysfunction, while limited effective pharmacological interventions remain currently available. This study investigated the protective effects of sodium butyrate (NaB), alone and in combination with newly i...

Fei-Yan Long, Jin-Yu Li, Yan-Ru Kang et al. · European Journal of Pharmaco... · 0 citations

Open access Aug 2026

Brucellar spondylitis is associated with disturbance in gut microbiota and histamine metabolism associated inflammation

Background The pathogenesis of brucellar spondylitis (BLS) has traditionally been considered to be primarily limited to local osteoarticular lesions. With the proposal of the “gut-spine axis” concept, the role of intestinal microecological dysbiosis in inflammatory spinal diseases has attracted in an increase of attent...

Zong-Jun Ma, Xiao-Yan Bai, Jun Tian et al. · Frontiers in Cellular and In... · 1 citation