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The DLRTransformer improved postoperative risk stratification compared with guideline-based risk stratification and identified patients with stage I NSCLC who benefited from adjuvant therapy.
Background Renal fibrosis, a common pathological endpoint in Chronic Kidney Disease (CKD), is closely associated with the accumulation of gut-derived uremic toxins, underscoring the therapeutic relevance of the gut-kidney axis. This study investigated the antifibrotic mechanism of Haikunshenxi Capsule (HKSX), a marine-...
Highlights • A macrophage-associated prognostic signature was developed for KIRC.• Prognostic genes were identified through Cox analysis and multi-algorithm screening.• An MRCS classifier was independently constructed using SLC11A1 and IFI30.• Survival stratification and validation were systematically performed.
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