Glioblastoma (GBM) remains difficult to control. Monoclonal antibodies (mAbs) have transformed the treatment of several extracranial cancers, but they have not consistently improved survival in GBM. This narrative review examines the main biological and translational barriers to antibody-based therapy. It also evaluate...
Yang Zhou, You-Ming Li, Yu Chen et al.· Current Oncology· 0 citations
Overall, MSTO1 plays an important role during the development of HCC, and it was also associated with survival or response to immunotherapy, and the progression of HCC may be associated with HSP90AB1 and MYC, and targeting MSTO1 may effectively enhance the efficacy of anti-PD-1 therapy.
Xiang-Dong Li, Hao-Liang Zhu, Min-Hao Chen et al.· International Immunopharmaco...· 0 citations
The current applications of direct neuronal reprogramming technology in several neurological diseases are discussed and the potential contamination issues in adeno-associated virus (AAV) delivery systems are highlighted and a code of conduct is proposed to avoid artifacts and pitfalls.
Yu Chen, Zhe Zheng, Pei-Lei Zhao et al.· Frontiers in Neuroscience· 0 citations
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