Hao-Heng Yu

Baseline mood and non-motor symptom burden are associated with cognitive progression in Parkinson’s disease: an interpretable follow-up cohort analysis with separate neuroimaging, molecular, and digital analyses in independent samples

Clinically useful artificial intelligence and machine-learning studies in healthcare require interpretable features, internal validation, and explicit boundaries between primary inference and external context. Among 1,612 baseline Parkinson’s Progression Markers Initiative (PPMI) participants, 1,439 had evaluable post-...