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Open access Aug 2026

Exploration of the mechanism of gut microbiota-mediated immune modulation in the pathogenesis of pancreatic cancer

The pathogenesis of pancreatic cancer is complex. While immune dysregulation and gut microbiota disturbances are considered key factors, the causal pathway between them remains unclear. This study employs a 2-step Mendelian randomization (MR) approach to empirically investigate the “immune cells - gut microbiota - panc...

Meng-Yun Cai, Hao Cheng, Yaying Jia et al. · 0 citations
Aug 2026

High-Dimensional SERS Mapping of Single Circulating Tumor Cells Deciphers the Phenotypic Landscape and Stratifies Metastatic Risk in Pancreatic Cancer.

Applying PRISM to CTCs from pancreatic cancer patients, a novel data analysis framework is introduced, including a 'Metastasis Potential Score' (MPS), to translate high-dimensional spectral data into a clinically relevant metric for risk stratification.

Yanrong Wen, Mengxiang Liu, Chun-Hui Liu et al. · 0 citations

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