Hans-Christian Siebert

Targeting Microglial HDAC3 Enhances Aβ Clearance and Neuroprotection in APP/PS1 Mice: A Ketogenic Diet‐Driven Strategy

It is reported that a 12‐week ketogenic diet treatment ameliorated cognitive deficits, reduced amyloid‐β (Aβ) deposition and tau hyperphosphorylation, and attenuated neuroinflammation in male APP/PS1 mice, suggesting a novel mechanism by which KD exerts neuroprotective effects through modulation of the microglial HDAC3...