In-silico Identification of Cyclic Peptide Inhibitors for A42r Profilin-like Protein from Monkeypox Virus.
INTRODUCTION The emergence of Monkeypox Virus (MPXV) as a major global health concern underscores an urgent unmet need for innovative antiviral therapeutics. To address this need, a novel large-scale in silico screening strategy was adopted to identify highly potent antiviral cyclic peptides that inhibit the A42R profi...