Open access
Jul 2026
Enhanced replication and immunogenicity of a genome-modified non-replicating vaccinia virus Tiantan strain for robust low-dose protection in mice
It is demonstrated that NTV-ΔF1L-C7L combines high safety with enhanced replication and immunogenicity, supporting its value as a novel vaccine vector and its potential application in controlling the current global monkeypox outbreak.
Jiao Ren, Shi-Yuan Liu, Hang Yuan et al.
· Journal of Virology · 0 citations