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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Hang Li

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Aug 2026

Discovery and Biosynthesis of Brasilanes G−L: N -Acetylglucosamine-Decorated Sesquiterpenoids with Anti-Inflammatory Activity

This study expands the chemical space of GlcNAc-conjugated terpenoids and showcases a biosynthetic logic in which enzymatic tailoring is coupled with nonenzymatic reactions to amplify both structural diversity and biological properties.

Ming-Min Wu, Yao-Hui Shi, Yu-Wei Lin et al. · 0 citations
Aug 2026

Radical Mechanism and Stereochemical Control in Consecutive C-C Bond Formation by the Nonheme Iron Enzyme Hvm1.

Iron(II)/2-oxoglutarate-dependent (Fe/2OG) enzymes catalyze consecutive C-C bond formations to assemble complex heterobicyclic ring systems and generate three new stereocenters in piperazine alkaloids helvamide B and the arizonamides through C(sp3)-H activation─a transformation that remains challenging in synthetic che...

Shengbin Zhou, Jia-Peng Zhang, Jia-Yu Zuo et al. · 0 citations

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