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Open access Oct 2026

Single-cell transcriptomics links HPV transcript abundance to malignant epithelial heterogeneity and redistribution of cell-cell communication across cervical lesions

Persistent high-risk Human Papillomavirus (HPV) infection is a prerequisite for most cervical cancers, but only a subset of infections progress to invasive disease. This study investigated associations between HPV transcript abundance, malignant epithelial heterogeneity, inferred cell-state trajectories, and microenvir...

Han Zhang, Wei Chen, Ya-Ping Li et al. · 0 citations

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