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Open access Sep 2026

Effects of Yijing decoction on diminished ovarian reserve: associations with mitochondrial function, apoptosis, and the PGC-1α/SIRT3/HIF-1α pathway

Diminished ovarian reserve (DOR) is a common reproductive disorder that severely impairs female fertility and lacks effective treatments. Protecting granulosa cells (GCs) has emerged as a promising therapeutic strategy. Yijing decoction (YJD), a classical Chinese herbal formula, exhibits clinical efficacy against D...

Jia-Qi Yang, Xiu-Ting Mo, Meng-Yuan Chu et al. · 0 citations
Review Open access Aug 2026

Restoring glucose metabolic homeostasis to attenuate ovarian aging: mechanisms and clinical prospects

This review summarizes recent advances in understanding the ovarian glucose metabolic network, metabolite-driven post-translational modifications, and the interplay among various pathological mechanisms and explores potential regulators that could restore glucose metabolic balance.

Gen-Ping Zeng, Meng-Yuan Chu, Jia-Qi Yang et al. · 0 citations

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