Author

Han Shu

2 papers indexed here

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Open access Aug 2026

SpatialMOC: Accurate reconstruction of spatial multi-omics landscapes through cross-modality prediction

Across multiple tissues, molecular modalities, developmental stages, sequencing platforms, and degraded datasets, SpatialMOC consistently outper-formed existing computational approaches in bidirectional molecular prediction and establishes SpatialMOC as a general framework for spatial multi-omics reconstruction.

Zhengxuan Liu, Peimeng Zhen, Bingtao Wang et al. · bioRxiv · 0 citations

Jul 2026

Mosaic integration of spatial multiomic data based on hierarchical graph contrastive learning with SpatialMOSI.

SpatialMOSI provides a critical computational foundation for constructing integrative 3D molecular atlases from complex multimodal spatial data sets and demonstrates SpatialMOSI's versatility across multiple biological systems, accurately identifying spatially conserved domains, imputing missing omic layers, and recons...

Peimeng Zhen, Han Shu, Bingtao Wang et al. · Genome Research · 0 citations