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Author

Han-Shi Guo

3 papers indexed here

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Sep 2026

Yindan-Pinggan Capsules Alleviate Steatotic Liver Disease Through Modulating Multiple Signaling Pathways in Mice.

INTRODUCTION Steatotic Liver Disease (SLD), including Alcohol-Associated Liver Disease (ALD) and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), is one of the most prevalent chronic liver diseases globally, affecting approximately a quarter of the world's population. It poses a significant burden on g...

Yong Zhang, Bei Li, Jun-Jie Zhang et al. · 0 citations
Open access Sep 2026

Histone demethylase JMJD2D promotes macrophage IL-12b expression and contributes to host defense against Listeria monocytogenes infection.

Introduction Listeria monocytogenes (L. monocytogenes) is an intracellular bacterial pathogen that requires coordinated innate and adaptive immune responses for effective clearance. However, the epigenetic mechanisms governing host defense against L. monocytogenes remain poorly understood. Methods JMJD2D-deficient mi...

Yi-Lin Hong, Han-Shi Guo, Bei Li et al. · 0 citations
Sep 2026

Yindan Pinggan Capsule Suppresses Hepatocellular Carcinoma Proliferation via TGR5-mediated Dual Inhibition of YAP and Hedgehog Pathways.

It is demonstrated that YDPG suppresses HCC progression through activation of TGR5 and simultaneous inhibition of the YAP and Hedgehog signaling pathways, and enhances the anti-tumor efficacy of Sorafenib, highlighting its translational potential as an adjuvant therapeutic strategy for HCC.

Yi-Lin Hong, W. Xi, Han-Shi Guo et al. · 0 citations

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