Author

Han-Fu Zhang

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Open access Sep 2026

Two-photon light-sheet microscopy with isotropic near-diffraction-limited resolution in three dimensions

Summary Achieving isotropic high-resolution three-dimensional imaging across a large field of view (FOV) remains a key challenge in two-photon light-sheet microscopy (TPLSM). To address this limitation, we developed a TPLSM system that stitches multiple short Bessel beams into a large, ultrathin illumination light shee...

Xing-Yun Zhang, Le-Qiang Yang, Wen-Yu Wang et al. · iScience · 0 citations

#machine learning Preprint Sep 2026

Riemannian Difference-of-Convex Optimization for K-Means Clustering

K-means is a widely adopted clustering approach in signal processing and machine learning. In this paper, we study K-means clustering through a cardinality-constrained formulation on a compact embedded submanifold. We replace the cardinality constraint with a difference-of-convex (DC) penalty and establish a global err...

Meng Xu, Bo Jiang, Han-Fu Zhang et al. · 0 citations